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Cellular delivery and antisense effects of peptide nucleic acid conjugated to polyethyleneimine via disulfide linkers
Peter R Berthold, Takehiko Shiraishi,
Peter E Nielsen
Transcription, RNA, and Gene Medicine Program
Institut for Cellulær og Molekylær Medicin
24
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Medicin og biovidenskab
Amines
5%
Chloroquine
5%
Cysteine
4%
Disulfides
49%
DNA
2%
HeLa Cells
5%
High-Throughput Screening Assays
7%
Luciferases
4%
N-succinimidyl 3-(2-pyridyldithio)propionate
18%
octaarginine
9%
Peptide Nucleic Acids
68%
Polyethyleneimine
62%
Polymers
4%
RNA
3%
Transfection
8%
Teknik og materialevidenskab
Amines
6%
Assays
12%
DNA
5%
Molecules
5%
Peptide Nucleic Acids
100%
Polyethylene glycols
13%
Polymers
3%
Purification
5%
RNA
6%
Scaffolds
6%
Screening
4%
Throughput
3%
Toxicity
6%
Kemiske forbindelser
Chloroquine
8%
Cysteine
5%
Disulfide
38%
High Throughput Screening
7%
Modification
3%
Molecule
2%
Nucleic Acid
5%
Peptide
3%
Peptide Nucleic Acid
58%
Propionate
7%
Purification
4%