Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

Daniella Bach Pedersen, Peter Koch Jensen, Morten la Cour, Jens Folke Kiilgaard, Thor Eysteinsson, Kurt Bang, Anne Kathrine Wiencke, Einar Stefánsson

    53 Citationer (Scopus)

    Abstract

    Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.
    OriginalsprogEngelsk
    TidsskriftGraefe's Archive for Clinical and Experimental Ophthalmology
    Vol/bind243
    Udgave nummer2
    Sider (fra-til)163-8
    Antal sider6
    ISSN0721-832X
    DOI
    StatusUdgivet - 2005

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