Binding and Orientation of Tricyclic Antidepressants within the Central Substrate Site of the Human Serotonin Transporter

Medicin og biovidenskab

• Amines 10%
• Antidepressive Agents 9%
• Binding Sites 39%
• Imipramine 24%
• Leucine 20%
• Ligands 14%
• Mutagenesis 10%
• Mutation 5%
• Proteins 3%
• Salts 8%
• Serotonin 8%
• Serotonin Plasma Membrane Transport Proteins 88%
• Structural Models 11%
• Tricyclic Antidepressive Agents 83%

Kemiske forbindelser

• Amine 6%
• Antidepressant 12%
• Binding Site 35%
• Imipramine 27%
• Leucine 21%
• Ligand 4%
• Mutation 8%
• Serotonin 78%
• Tricyclic Antidepressant Agent 100%