Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

Tina Kold Jensen; Niels Erik Skakkebæk; Niels Jørgensen; Martin Blomberg Jensen; Anders Juul

Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

Tina Kold Jensen, Niels Erik Skakkebæk, Niels Jørgensen, Martin Blomberg Jensen, Anders Juul

2 Citationer (Scopus)

Abstract

In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.

Bidragets oversatte titel	Antioxidants and male subfertility--a survey of a Cochrane review
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	173
Udgave nummer	50
Sider (fra-til)	3253-5
Antal sider	3
ISSN	0041-5782
Status	Udgivet - dec. 2011

Citationsformater

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title = "Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview",

abstract = "In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.",

author = "Jensen, {Tina Kold} and Skakkeb{\ae}k, {Niels Erik} and Niels J{\o}rgensen and Jensen, {Martin Blomberg} and Anders Juul",

year = "2011",

month = dec,

language = "Dansk",

volume = "173",

pages = "3253--5",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

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TY - JOUR

T1 - Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

AU - Jensen, Tina Kold

AU - Skakkebæk, Niels Erik

AU - Jørgensen, Niels

AU - Jensen, Martin Blomberg

AU - Juul, Anders

PY - 2011/12

Y1 - 2011/12

N2 - In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.

AB - In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.

M3 - Kommentar/debat

SN - 0041-5782

VL - 173

SP - 3253

EP - 3255

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 50

ER -

Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

Abstract

Fingeraftryk

Citationsformater