An improved method for the detection of peptide-induced upregulation of HLA-A2 molecules on TAP-deficient T2 cells

M Regner, Mogens Helweg Claesson, S Bregenholt, M Röpke

21 Citationer (Scopus)

Abstract

Peptide-induced upregulation of MHC class I on TAP-deficient T2 cells is used to monitor peptide binding to class I molecules. We present a temperature-dependent modification of the T2 assay which increases the sensitivity of peptide binding to MHC class I with several orders of magnitude.
OriginalsprogEngelsk
TidsskriftExperimental and Clinical Immunogenetics
Vol/bind13
Udgave nummer1
Sider (fra-til)30-5
Antal sider6
ISSN0254-9670
StatusUdgivet - 1 jan. 1996

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