Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis

L Andresen, V.L. Jørgensen, A. Perner, A. Hansen, J Eugen-Olsen, Jørgen Rask-Madsen, L Andresen, V L Jørgensen, A Perner, A Hansen, J Rask-Madsen

    138 Citationer (Scopus)

    Abstract

    Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.
    OriginalsprogEngelsk
    TidsskriftGut
    Vol/bind54
    Udgave nummer4
    Sider (fra-til)503-9
    Antal sider7
    ISSN0017-5749
    DOI
    StatusUdgivet - 2005

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