A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome

Medicin og biovidenskab

• Blood Vessels 5%
• Brittle cornea syndrome 1 100%
• Carrier Proteins 8%
• Chromatin 4%
• Chromatin Immunoprecipitation Sequencing 6%
• Connective Tissue Diseases 5%
• DNA Methylation 4%
• Epigenomics 8%
• Exons 16%
• Extracellular Matrix 8%
• Eye 6%
• Fibroblasts 18%
• Gene Ontology 5%
• Genes 5%
• heterochromatin-specific nonhistone chromosomal protein HP-1 15%
• Histones 4%
• Immunohistochemistry 6%
• Immunoprecipitation 4%
• Mass Spectrometry 4%
• Methylation 44%
• Mi-2 Nucleosome Remodeling and Deacetylase Complex 8%
• Mutation 8%
• Phenotype 2%
• Polymerase Chain Reaction 2%
• PR-SET Domains 74%
• Protein Binding 9%
• Proteins 1%
• Retina 4%
• Retinal Vessels 5%
• Skin 8%
• Staining and Labeling 3%
• Transcription Factors 3%
• Up-Regulation 3%
• Western Blotting 3%