4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists

Jean-Marie Receveur, Emelie Bjurling, Trond Ulven, Paul Brian Little, Pia K Nørregaard, Thomas Högberg

    46 Citationer (Scopus)

    Abstract

    Synthesis, in vitro biological evaluation and structure-activity relationships of 4-acylamino-and 4-ureidobenzamides as novel hMCH1R-antagonists are disclosed. The nature of the amine side chains could be varied considerably in contrast to the central benzamide scaffold and aromatic substituents.
    OriginalsprogEngelsk
    TidsskriftBioorganic & Medicinal Chemistry Letters
    Vol/bind14
    Udgave nummer20
    Sider (fra-til)5075-5080
    Antal sider6
    ISSN0960-894X
    DOI
    StatusUdgivet - 18 okt. 2004

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