Ulrik Gether

Publikation

Publikationer pr. år 1990 1999 2001 2002 2003 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2019 2020

• 173 Tidsskriftartikel
• 8 Bidrag til bog/antologi
• 3 Review
• 2 Kommentar/debat
• 2 Mere
  • 1 Bidrag til rapport
  • 1 Konferenceabstrakt i tidsskrift

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2003

  Probing dopamine transporter structure and function by Zn2+-site engineering

  Loland, C. J., Norgaard-Nielsen, K. & Gether, U., 31 okt. 2003, I: European Journal of Pharmacology. 479, 1-3, s. 187-97 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Biogenic Amines 100%
  • Dopamine Plasma Membrane Transport Proteins 94%
  • Amphetamines 51%
  • Cocaine 38%
  • Antidepressive Agents 34%
  33 Citationer (Scopus)

• Probing dopamine transporter structure and function y Zn2+ site engineering

  Løland, C. J., Nørgaard-Nielsen, K. & Gether, U., 2003, I: European Journal of Pharmacology. Vol. 479, no 1-3, s. 187-97

  Publikation: Bidrag til tidsskrift › Review › peer review

• Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1.

  MacAulay, N., Meinild, A-K., Zeuthen, T. & Gether, U., 2003, I: Journal of Biological Chemistry. 278, 31, s. 28771-7 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Gamma-Aminobutyric Acid 100%
  • gamma-Aminobutyric Acid 80%
  • Oocytes 46%
  • Voltage 40%
  • Membrane Potential 30%
  11 Citationer (Scopus)

• Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy

  Rasmussen, S. G. F., Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, U., 31 okt. 2003, I: European Journal of Pharmacology. 479, 1-3, s. 13-22 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 8-methyl-3-(4-methylphenyl)tropane--2-carboxylic acid N-methyl-N-(4-nitrobenzo-2-oxa-1,3-diazol-7-yl)ethanolamine ester 100%
  • Biogenic Amines 80%
  • Fluorescence Spectrometry 78%
  • Serotonin Plasma Membrane Transport Proteins 76%
  • Cocaine 41%
  6 Citationer (Scopus)
• 2002

  Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1

  MacAulay, N., Zeuthen, T. & Gether, U., 15 okt. 2002, I: Journal of Physiology. 544, Pt 2, s. 447-58 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • gamma-Aminobutyric Acid 100%
  • Choline 44%
  • Water 41%
  • Binding Sites 32%
  • Protein Conformation 27%
  40 Citationer (Scopus)

• Conformational basis for the Li⁺- induced leak current in the rat ¿- aminobutyric acid (GABA) transporter- 1

  MacAulay, N., Zeuthen, T. & Gether, U., 2002, I: Journal of Physiology. 544, 2, s. 447-458

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  40 Citationer (Scopus)

• Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

  Loland, C. J., Norregaard, L., Litman, T. & Gether, U., 5 feb. 2002, I: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, s. 1683-8 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Dopamine Plasma Membrane Transport Proteins 100%
  • Tyrosine 74%
  • Dopamine 68%
  • Mazindol 65%
  • Mutation 45%
  113 Citationer (Scopus)

• Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

  Løland, C. J., Norregaard, L., Litman, T. & Gether, U., 2002, I: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), s. 1683-8

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Passive water and urea permeability of a human Na(+)-glutamate cotransporter expressed in Xenopus oocytes

  Macaulay, N., Gether, U., Klærke, D. A. & Zeuthen, T., 2002, I: Journal of Physiology. 542, 3, s. 817-828 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Xenopus 100%
  • Urea 89%
  • Oocytes 88%
  • Glutamic Acid 82%
  • Permeability 80%
  37 Citationer (Scopus)

• Structural basis for activation of G-protein-coupled receptors.

  Gether, U., Asmar, F., Meinild, A. K. & Rasmussen, S. G. F., 2002, I: Basic & Clinical Pharmacology & Toxicology. 91, 6, s. 304-12 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • G-Protein-Coupled Receptors 100%
  • Adrenergic Receptors 94%
  • Fluorescent Probe 46%
  • Cystic Fibrosis Transmembrane Conductance Regulator 41%
  • Xenopus laevis 38%
  73 Citationer (Scopus)

• The role of zinc ions in reverse transport mediated by monoamine transporters

  Scholze, P., Nørregaard, L., Singer, E. A., Freissmuth, M., Gether, U. & Sitte, H. H., 14 jun. 2002, I: Journal of Biological Chemistry. 277, 24, s. 21505-13 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Monoamine 100%
  • Serotonin 95%
  • Zinc Ion 92%
  • Zinc 83%
  • Dopamine 81%
  75 Citationer (Scopus)

• The role of zine ions in reverse transport mediated by monoamine transporters

  Scholze, P., Norregaard, L., Singer, E. A., Freissmuth, M., Gether, U. & Sitte, H. H., 2002, I: Journal of Biological Chemistry. 277, s. 21505-21513

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  75 Citationer (Scopus)

• Understanding G-protein coupled receptors and their role in the CNS

  Rasmussen, S. G. F. & Gether, U., 2002, Structural mechanics of GPCR activation. s. 43-62

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til rapport › Forskning

• Use of fluorescence spectroscopy to study conformational changes in the beta 2-adrenoceptor

  Kobilka, B. K. & Gether, U., 2002, I: Methods in Enzymology. 343, 343, s. 170-182 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  30 Citationer (Scopus)

• Zn(2+) site engineering at the oligomeric interface of the dopamine transporter

  Norgaard-Nielsen, K., Norregaard, L., Hastrup, H., Javitch, J. A. & Gether, U., 31 jul. 2002, I: FEBS Letters. 524, 1-3, s. 87-91 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Dopamine Plasma Membrane Transport Proteins 100%
  • Dopamine 76%
  • Neurotransmitter Transport Proteins 64%
  • Binding Sites 62%
  • Histidine 44%
  33 Citationer (Scopus)

• Zn(2+) site engineering oat the oligomeric interface of the dopamine transporter

  Nørgaard-Nielsen, K., Norregaard, L., Hastrup-Nielsen, H., Javitch, J. A. & Gether, U., 2002, I: FEBS Letters. vol. 524(1-3), s. 87-91

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
• 2001

  Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6

  Ballesteros, J. A., Jensen, A. D., Liapakis, G., Rasmussen, S. G. F., Shi, L. & Gether, U., 2001, I: Journal of Biological Chemistry. 276 (31), s. 29171-29177

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

  Jensen, A. D., Guarnieri, F., Rasmussen, S. G. F., Asmar, F., Ballesteros, J. A. & Gether, U., 2001, I: Journal of Biological Chemistry. 276 (12), s. 9279-9290

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

  Rasmussen, S. G. F., Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, U., 2001, I: Journal of Biological Chemistry. 276 (7), s. 4717-4723

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  27 Citationer (Scopus)

• Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites

  Gether, U., Norregaard, L. & Løland, C. J., 2001, I: Life Sciences. 68 (19-20), s. 2187-2198

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  7 Citationer (Scopus)

• Engineered Zn(2+)switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

  Macaulay, N., Bendahan, A., Løland, C. J., Zeuthen, T., Kanner, B. I. & Gether, U., 2001, I: Journal of Biological Chemistry. 276, s. 40476-40485

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  38 Citationer (Scopus)

• Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations

  Seifert, R., Wenzel-Seifert, K., Gether, U. & Kobilka, B. K., 2001, I: Journal of Pharmacology and Experimental Therapeutics. 297 (3), s. 1218-1226

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  95 Citationer (Scopus)

• Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

  Norregaard, L., Visiers, I., Løland, C. J., Ballesteros, J. A., Weinstein, H. & Gether, U., 2001, I: Biochemistry. 39 (51), s. 15836-15846

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Water transport by the human Na+-coupled glutamate cotransporter expressed in Xenopus oocytes

  Macaulay, N., Gether, U., Klaerke, D. A. & Zeuthen, T., 2001, I: Journal of Physiology. 530 (Pt 3), s. 367-378

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  70 Citationer (Scopus)
• 2000

  Assessing adrenergic receptor conformation using chemically reactive fluorescent probes

  Jensen Dam, A. & Gether, U., 2000, Methods in Molecular Biology, vol.126: Adrenergic Receptors Protocols. Totowa, NJ: Humana Press, s. 345-359

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

  1 Citationer (Scopus)

• The effect of pH on ß₂ adrenoceptor function

  Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, S. G. F., Gether, U. & Kobilka, B. K., 2000, I: Journal of Biological Chemistry. 5, Vol. 275, s. 3121-3127

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Uncovering molecular mechanism involved in activation of G protein-coupled receptors

  Gether, U., 2000, I: Endocrine Reviews. 21(1), s. 90-113

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  1073 Citationer (Scopus)
• 1999

  Assessing adrenergic receptor using chemically reactive fluorescent probes

  Dam Jensen, A. & Gether, U., 1999, In Adrenergic Receptor Protocols, in the Methods for Molecular Biology. Humana Press, s. 345-361

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

• Characterization of ligand-induced conformational states in the beta 2 adrenergic receptor

  Kobilka, B. K., Gether, U., Seifert, R., Lin, S. & Ghanouni, P., 1999, I: Journal of Receptors and Signal Transduction. 19, s. 293-300

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

  Løland, C. J., Norregaard, L. & Gether, U., 1999, I: Journal of Biological Chemistry. 274, 52, s. 36928-34 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Dopamine Plasma Membrane Transport Proteins 100%
  • Glutamic Acid 85%
  • Tertiary Structure 85%
  • Dopamine 76%
  • Binding Sites 62%
  100 Citationer (Scopus)

• Direct assessment of conformational changes in G protein coupled receptors using fluorescence spectroscopy

  Gether, U. & Kobilka, B. K., 1999, In Signal Transduction - A practical Approach, in The practical Approach series, 2nd edition. Oxford: Oxford University Press, s. 01-17

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

• Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations

  Seifert, R., Gether, U., Wenzel-Seifert, K. & Kobilka, B. K., 1999, I: Molecular Pharmacology. 56, s. 348-358

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  107 Citationer (Scopus)

• Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-Gsalpha fusion protein

  Seifert, R., Wenzel-Seifert, K., Gether, U., Lam, V. T. & Kobilka, B. K., 1999, I: European Journal of Biochemistry. 260, s. 661-666

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  32 Citationer (Scopus)

• Fluorescence spectrosocpy analysis of conformational changes in the Β2 adrenergic receptor

  Gether, U., 1999, In Structure/Function of G-protein coupled receptors, in the Receptor Biochemistry and Methodology. New York: Wiley, s. 315-334

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

• Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI

  Rasmussen, S. G. F., Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, U., 1999, I: Molecular Pharmacology. 56, s. 175-184

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
• 1998

  Delineation of an endogenous zinc-binding site in the human dopamine transporter.

  Norregaard, L., Frederiksen, D., Nielsen, E. Ø. & Gether, U., 1998, I: EMBO Journal. 17, s. 4266-4273

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  132 Citationer (Scopus)
• 1990

  [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

  Fuhlendorff, J., Gether, U., Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, O. & Schwartz, T. W., 1990, I: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, s. 182-6 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Neuropeptide Y 100%
  • Neuroblastoma 17%
  • neuropeptide Y (13-36) 15%
  • Neuropeptide Y Receptors 12%
  • Binding Sites 6%
  370 Citationer (Scopus)

• Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

  Aakerlund, L., Gether, U., Fuhlendorff, J., Schwartz, T. W. & Thastrup, O., 1990, I: F E B S Letters. 260, 1, s. 73-8 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • neuropeptide Y-Y1 receptor 100%
  • Neuropeptide Y 95%
  • Adenylyl Cyclases 65%
  • Calcium(0) 49%
  • Calcium 43%
  127 Citationer (Scopus)